Experts call for vaccination, antibiotics in Haiti

WASHINGTON, (Reuters) – Simply setting up clinics to  treat Haitians with cholera is not doing anywhere near enough  to tackle the epidemic there, health experts said yesterday,  calling for intensive vaccination and more use of antibiotics.

Their recommendation, published in the Lancet medical  journal, adds to a growing chorus of voices speaking in support  of a vaccination program.

Health authorities, including the Pan-American Health  Organization, had argued against vaccination, saying it would  be too difficult and expensive.

But Paul Farmer of Harvard Medical School and colleagues at  his organization Partners In Health said current strategies are  not working.

“Rehydration alone without any antibiotics, in our view, is  not a good idea, even for moderate cases of cholera,” Farmer  told reporters in a telephone briefing.

Haiti’s health ministry reports that more than 91,000  people have been sickened by cholera since the outbreak began  in October, with more than 2,000 deaths. More than 3 percent of  patients are dying — a high death rate for cholera.

Cholera is caused by a water-borne bacteria called Vibrio  cholerae. It is transmitted when contaminated human fecal  matter gets into water, food or onto someone’s hands.

Many people show no symptoms but can pass it along and  cholera can cause extremely severe diarrhea and vomiting that  will kill within hours by dehydrating victims.

Standard treatment is a rehydration fluid containing  special sugars and salts but Farmer’s team said this is not  doing enough in Haiti.

“Sometimes we are seeing them really late, when they are  very ill and being carried in. Treatment needs to be much more  aggressive,” Farmer said.

PAHO, the American division of the World Health  Organization, has opposed vaccination. But earlier on Thursday  PAHO’s Dr. Jon Andrus told NPR that his organization had  discovered more than 1 million doses of oral cholera vaccine  stockpiled and was rethinking its stance.

Sanofi Aventis’ India-based division Shantha makes a  vaccine called Shanchol for about $1 a dose, with up to three  doses needed for protection, while Netherlands-based Crucell  makes another oral vaccine called Dukoral.

“Both Shanchol and Dukoral are needed here, and production  of these vaccines should be ramped up, as cholera experts have  argued for the past decade,” Farmer’s team wrote.

They said workers vaccinated Haitian girls against HPV —  with better success than in some U.S. cities. HPV vaccination  requires three shots, so Farmer said there is no basis for  arguing cholera vaccination is too difficult in Haiti.

Many Haitians suspect United Nations troops, specifically a  team from Nepal, brought cholera to Haiti.

Detailed genetic tests show only that the cholera strain  came from South Asia and most closely resembles a strain  circulating in Bangladesh.

Harvard experts who published that report on Thursday are  also calling for vaccination in Haiti.

Aid workers from more than 10,000 organizations all over  the world have poured into Haiti to help after a devastating  January earthquake, which leveled much of the capital and  killed 250,000 people.

Adding to the uncertainty in Haiti are the disputed results  of last month’s election there that have triggered nationwide  unrest.