US scientists recreate heart defect in a lab dish

CHICAGO, (Reuters) – Using skin cells taken from  children with a rare heart defect, U.S. researchers have  created beating heart cells in the lab with the same heart  defect, allowing researchers to test new drugs in human cells  instead of mice.

While most heart drugs had no effect on the cells, a cancer  drug being studied by Cyclacel Pharmaceuticals Inc appears to  help, the team led by Ricardo Dolmetsch of Stanford University  reported on Wednesday in the journal Nature.

The study is among the first to use powerful new technology  to create human models of disease by reprogramming ordinary